CASE 1: Mrs. Denise Lachance, a 63-year-old retired teacher, has rheumatoid arthritis treated with methotrexate 15 mg (six 2.5 mg tablets) once a week, folic acid 1 mg daily, and naproxen 250 mg twice daily when needed. Her morning joint stiffness lasts about 2 hours, and her wrists and finger joints are swollen. She has generalized 4-5 mm pockets with bleeding. Her prescriptions were recently transferred to a new pharmacy. For 8 days she has had painful ulcers on her tongue and buccal mucosa, a sore throat and marked tiredness. The label on her new methotrexate bottle is shown in the image. What is the MOST appropriate action?